CoReNe: Control of Regulatory Networks with focus on non-coding RNA
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Network Coordinators:
Prof. Dr. Hans-Werner Mewes, Helmholtz Zentrum München
Prof. Dr. Wolfgang Wurst, Helmholtz Zentrum München(Deputy Coordinator)
Project Overview:
The interdisciplinary network entitled CoReNe focuses on the integrative interpretation of regulatory networks involved in cell differentiation with focus on the interaction of non-coding RNAs (ncRNAs). Here, the function of ncRNAs is viewed as interference with gene expression (mostly siRNAs).
CoReNe is organized as a network joining molecular biology with theoretical modules organized around a Systems Biology core group headed by Dr. Fabian Theis.
CoReNe wants to focus on distinct aspects of the role of ncRNAs in regulatory networks:
i. the functional interaction of ncRNAs with the systems and sub-systems investigated
ii. the time and space dependency of nc-RNA action
iii. the integration of ncRNAs in qualitative and quantitative models for regulatory networks
Further information on CoReNe can be found under on the networks homepage.
Further Project Leaders:
- Fabian Theis, Research Group Computational Modeling in Biology, Institute for Bioinformatics and Systems Biology
Helmholtz Zentrum München - Frank Allgöwer, Univ. Stuttgart Institute of Systems Theory and Automatic Control
- Martina Götz, Inst. of Stem Cell Research, Helmholtz Zentrum München
- Martin Hrabé de Angelis, Inst. of Experimental Genetics, Helmholtz Zentrum München
- Rupert Lasser, Inst. f. Biomathematics and Biostatistics, Helmholtz Zentrum München
- Thomas Meitinger, Inst. of Human Genetics, Helmholtz Zentrum München
- Hans-Werner Mewes, Institute for Bioinformatics and Systems Biology
Helmholtz Zentrum München - Günther Schütz, DKFZ, Division Mol. Biology of the Cell 1
- Ralf Zimmer, Univ. München, Department of Informatics LFE Bioinformatics
