Helmholtz Association

11. December 2012 Helmholtz Centre for Infection Research

Phagocytes ingest particles as well as pathogens from their surroundings into compartments called phagosomes. The phagosomes possess a harsh milieu with microbicidal function; therefore the phagocytes represent the first line of defense against infections. However, some intracellular pathogens, including members of mycobacterial species, manipulate the phagosomes to survive within them.

New insights on phagosome maturation

Phagocytes ingest particles as well as pathogens from their surroundings into compartments called phagosomes. The phagosomes possess a harsh milieu with microbicidal function; therefore the phagocytes represent the first line of defense against infections. However, some intracellular pathogens, including members of mycobacterial species, manipulate the phagosomes to survive within them.

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13.01.2013