Helmholtz Association

06. December 2012 German Cancer Research Centre

Natural killer cells (or NK cells), as part of the body´s immune system, can effectively fight cancer. Unfortunately, they quickly lose their aggressiveness and hence are unable to reject solid tumors. Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now discovered a cocktail consisting of three different immune mediators that leaves NK killer cells active over a long period of time. In mice, cocktail-boosted NK cells let tumors shrink. The cocktail was able to persistently activate human NK cells, too.

Cocktail Boosts Immune Cells in Fighting Cancer

Natural killer cells (or NK cells), as part of the body´s immune system, can effectively fight cancer. Unfortunately, they quickly lose their aggressiveness and hence are unable to reject solid tumors. Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now discovered a cocktail consisting of three different immune mediators that leaves NK killer cells active over a long period of time. In mice, cocktail-boosted NK cells let tumors shrink. The cocktail was able to persistently activate human NK cells, too.

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13.01.2013