28.11.2012 German Cancer Research Centre

How Aggregated Proteins Can Return to Their Original Shape

Anybody knows the process that happens when you cook an egg: The initially liquid and transparent egg white turns solid and opaque. Heidelberg scientists from the Center for Molecular Biology (ZMBH) at Heidelberg University and the German Cancer Research Center (DKFZ) have now discovered and unraveled a repair system used by cells to revert this protein aggregation. Experts from the Heidelberg Institute for Theoretical Studies (HITS) also participated in the research project. The scientists have now reported their research results in two simultaneously published articles in the specialist journal “Nature Structural and Molecular Biology”.

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