Helmholtz Association

03.08.2012 Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch

Acute liver failure is a life-threatening disease, characterized by a sudden, massive death of liver cells. Unfortunately, few treatment options exist, especially for advanced-stage liver failure. As a last resort a liver transplant may be the only remaining option. Now the physician Dr. Junfeng An of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and Dr. Stefan Donath, a specialist in internal medicine and cardiology, also of the MDC and Helios Klinikum Berlin-Buch, have developed a new treatment approach based on a mouse model. In their current study the liver failure was reversed and the mice recovered completely. The researchers hope to soon be able to test their new approach in clinical trials with patients.

MDC Researchers Develop New Approach to Treat Acute Liver Failure

Acute liver failure is a life-threatening disease, characterized by a sudden, massive death of liver cells. Unfortunately, few treatment options exist, especially for advanced-stage liver failure. As a last resort a liver transplant may be the only remaining option. Now the physician Dr. Junfeng An of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and Dr. Stefan Donath, a specialist in internal medicine and cardiology, also of the MDC and Helios Klinikum Berlin-Buch, have developed a new treatment approach based on a mouse model. In their current study the liver failure was reversed and the mice recovered completely. The researchers hope to soon be able to test their new approach in clinical trials with patients.

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13.01.2013

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