In Brief
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Brain Tumours and Genome
A mutation in the gene encoding the protein p53, the "Guardian of the Genome", results in a downright explosive rearrangement of large parts of the genetic material of cancer cells. Scientists from the DKFZ and the EMBL discovered this when examining a particularly aggressive group of brain tumours in children. Apparently, the chromosome explosion renders cells particularly prone to degenerating into cancer cells.


